Endocrine Abstracts

Background: Cushing’s syndrome (10-15/million people diagnosed/year) is quite rare with Cushing’s disease accounting for >70% of cases in adults. Spinal epidural lipomatosis (SEl) secondary to endogenous Cushing’s syndrome is even more rare condition (8 reported cases so far) of which 3 cases are secondary to Cushing’s disease. Here, we highlight a case of ACTH-dependent Cushing disease with resultant spinal epidural lipomatosis (SEl) that was treated w...

Introduction: Prevalence of prolactinoma is approximately 10/100,000 (men) and 30/100,000 (women) and dopamine agonists remain pharmacological treatment of choice. Cabergoline, an effective dopamine agonist, is preferred due to better tolerability withhigher efficacy in lowering prolactin and reducing tumour size in comparison with bromocriptine. Digital vasospasm, known adverse effect of Bromocriptineis mediated by activation of α1 adrenergic receptors. ...

Background: Cushing’s syndrome is rare (1.8-3.2 cases/million population)1, with Cushing’s disease (CD) accounting >70%. We seek to highlight a rare complication, spinal epidural lipomatosis (SEL), rare cause of spinal compression (prevalence-2.5%2), commonly related to exogenous steroid use with 3 reported cases secondary to CD3,4,5.Case: 36-years old man, background asthma and alcohol excess presented wit...

Section 1: Case history: A 78 years old lady presented to Emergency Department with two weeks history of lethargy and confusion. She had background of advanced destructive Rheumatoid Arthritis diagnosed 30 years ago, multiple joint fractures, osteoporosis, long-term urinary catheter, recurrent UTI and renal calculi. She was recently discharged from hospital for urosepsis. She was bed-bound for the last 15 years after crushing vertebrae C2 C3 pressing on spinal cord. Her regula...